The NALM-6 mannequin, a useful instrument in preclinical leukemia analysis, includes the implantation of human acute lymphoblastic leukemia cells into immunodeficient mice. This creates a dwelling system that mirrors the development and response to remedy seen in human leukemia, permitting researchers to review the illness and take a look at potential remedies in a extra managed setting.
This mannequin’s growth supplied researchers with a crucial platform for testing new therapies and finding out leukemia growth. It permits for detailed evaluation of illness development, drug resistance mechanisms, and the interplay between leukemia cells and the microenvironment. The power to check potential remedies in vivo earlier than scientific trials presents a extra environment friendly and moral method to drug growth, contributing to the development of leukemia therapy.
